4 years ago

Frontispiece: β2, 2-Amino Acid N-Carboxyanhydrides Relying on Sequential Enantioselective C(4)-Functionalization of Pyrrolidin-2,3-diones and Regioselective Baeyer–Villiger Oxidation

Frontispiece: β2, 2-Amino Acid N-Carboxyanhydrides Relying on Sequential Enantioselective C(4)-Functionalization of Pyrrolidin-2,3-diones and Regioselective Baeyer–Villiger Oxidation
Eider Badiola, Ana Vázquez, Claudio Palomo, Antonia Mielgo, Silvia Vera, Iurre Olaizola
Expanding the field: A simple metal free machinery comprised by an organocatalytic Michael reaction of pyrrolidin-2,3-diones and a regioselective Baeyer–Villiger rearrangement of the resultant adducts is reported en route to β2,2-amino acid coupled products. For more details, see the Full Paper by C. Palomo et al. on page 8185 ff.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201783464

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