Revealing a Role for NMDA Receptors in Regulating STN Inputs following the Loss of Dopamine
In this issue of Neuron, Chu et al. (2017) show that dopamine depletion using a 6-OHDA model causes a decrease in hyperdirect inputs from the motor cortex directly to the STN and that rescuing this loss alleviates Parkinsonian symptoms.
Publisher URL: http://www.cell.com/neuron/fulltext/S0896-6273(17)30784-5
DOI: 10.1016/j.neuron.2017.08.041
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