Take DAT, Flu!
Some microbial metabolites can be immunomodulatory, but there is limited understanding of how these contribute to inter-individual variation in response to infection. In a recent study in Science, Steed et al. (2017) show that the bacterial metabolite desaminotyrosine (DAT) increases type I interferon expression, resulting in an improved immune response to influenza infection.
Publisher URL: http://www.cell.com/immunity/fulltext/S1074-7613(17)30379-5
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