Organic Letters
Organic Letters
5 years ago

Chiral Selenide-Catalyzed Enantioselective Construction of Saturated Trifluoromethylthiolated Azaheterocycles

Chiral Selenide-Catalyzed Enantioselective Construction of Saturated Trifluoromethylthiolated Azaheterocycles
Yannan Liu, Jie Luo, Xiaodan Zhao
An indane-based, bifunctional, chiral selenide catalyst has been developed. The new catalyst is efficient for the enantioselective synthesis of saturated azaheterocycles possessing a trifluoromethylthio group. The desired products were obtained in good yields with high diastereo- and enantioselectivities.

Publisher URL: http://dx.doi.org/10.1021/acs.orglett.7b01392

DOI: 10.1021/acs.orglett.7b01392

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