3 years ago

Functionalized SBA-15 for controlled release of poorly soluble drug, Erythromycin

Functionalized SBA-15 for controlled release of poorly soluble drug, Erythromycin
SBA-15 was functionalized by 12-tungstophosphoric acid followed by loading of poorly water soluble drug, Erythromycin and Characterized by various physicochemical techniques such as TGA, FT-IR, Nitrogen adsorption-desorption, XRD and TEM. In-vitro controlled release studies of Erythromycin in Simulated Body Fluid were carried out under stirring as well as static conditions. In order to see the influence of inorganic moiety on release rate of drug, study was also carried out with Erythromycin loaded unfunctionalized SBA-15. A study on release mechanism and release kinetics using Higuchi model, Koresmeyer-Peppas model and Extended kinetic model shows that 12-tungstophosphoric acid has significant influence on the release rate of Erythromycin.

Publisher URL: www.sciencedirect.com/science

DOI: S1387181117306169

You might also like
Never Miss Important Research

Researcher is an app designed by academics, for academics. Create a personalised feed in two minutes.
Choose from over 15,000 academics journals covering ten research areas then let Researcher deliver you papers tailored to your interests each day.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.