5 years ago

Magnesium-Catalyzed Electrophilic Trifluoromethylation: Facile Access to All-Carbon Quaternary Centers in Oxindoles

Magnesium-Catalyzed Electrophilic Trifluoromethylation: Facile Access to All-Carbon Quaternary Centers in Oxindoles
Dmitry Katayev, Harutake Kajita, Antonio Togni
Invited for the cover of this issue is Dmitry Katayev and co-workers from the group of Antonio Togni at the Swiss Federal Institute of Technology in Zürich. The image depicts a magnesium salt as a key player that is able to perform the direct electrophilic trifluoromethylation of 3-substituted oxindoles. Read the full text of the article at 10.1002/chem.201700851. “…no matter how difficult a task, a deep reflection on the choice of the metal catalyst leads to the right move…” Read more about the story behind the cover in the Cover Profile and about the research itself on page 8353 ff. (DOI: 10.1002/chem.201700851).

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201701424

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