Chemical Communications
Chemical Communications
5 years ago

N-Difluoromethyl-triazole as a constrained scaffold in peptidomimetics

N-Difluoromethyl-triazole as a constrained scaffold in peptidomimetics
G. Bernadat, R. S. B. Goncalves, T. Milcent, F. Blanchard, M. Mamone, S. Ongeri, B. Crousse
The N-difluoromethyl triazolo-[small beta]-aza-ε-amino acid present in the core of peptides led to constrained conformations due to CH-F and NH-F interactions.

Publisher URL: http://feeds.rsc.org/~r/rss/CC/~3/hUe60UC8AqM/C7CC01298E

DOI: 2017/CC/C7CC01298E

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