Tetrahedron
Tetrahedron
5 years ago

Synthesis of spiroindolone scaffolds by Pictet-Spengler spirocyclisation using β-cyclodextrin-SO3H as a recyclable catalyst

Synthesis of spiroindolone scaffolds by Pictet-Spengler spirocyclisation using β-cyclodextrin-SO3H as a recyclable catalyst
A recyclable catalyst, β-cyclodextrin-SO3H in aqueous medium was used effectively for the synthesis of spiroindolones (tetrahydrospiro-β-carbolines as well as tetrahydrospiro-γ-carbolines) in a Pictet-Spengler spirocyclisation. The products were obtained in good yield in an environmental friendly procedure.

Publisher URL: www.sciencedirect.com/science

DOI: S0040402017305987

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