3 years ago

Disentangling the manifold functions of RORγt

Thomas Korn

A two-amino-acid substitution in the transcription factor RORγt disrupts its effect in establishing the transcriptional program of TH17 cells while leaving its function in the development of thymocytes and lymphoid-tissue–inducer cells largely intact.

Publisher URL: http://dx.doi.org/10.1038/ni.3831

DOI: 10.1038/ni.3831

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