3 years ago

Regenerative medicine: Breaking Prometheus's curse for cartilage regeneration

Florence Apparailly

Like the mythical eagle devouring Prometheus's liver as fast as it regrew, chronic inflammation hinders cartilage regeneration in inflammatory arthritis. Using stem cells engineered to secrete anti-inflammatory molecules in response to local inflammatory factors could provide a way to keep the eagle at bay as the stem cells differentiate into chondrocytes.

Publisher URL: http://dx.doi.org/10.1038/nrrheum.2017.116

DOI: 10.1038/nrrheum.2017.116

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