5 years ago

Loop diuretics are K+-sparing in the presence of a low-Na+, high-K+ diet

Under most conditions, loop diuretics are K+-wasting, requiring potassium supplementation. In this issue, Wang and colleagues demonstrate that in mice fed a low-Na+, high-K+ diet, loop diuretics, in contrast, are K+-sparing. This observation suggests that possible elevations in plasma K+ should be monitored when using a loop diuretic with a low-Na+, high-K+ diet, particularly when in combination with a potassium supplement.

Publisher URL: www.sciencedirect.com/science

DOI: S0085253817303885

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