3 years ago

Combinatorial Particle Patterning

Combinatorial Particle Patterning
Clemens von Bojnicic-Kninski, Edgar Dörsam, Alexander Nesterov-Mueller, Frank Breitling, Felix F. Loeffler, Roman Popov
The unique properties of solid particles make them a promising element of micro- and nanostructure technologies. Solid particles can be used as building blocks for micro and nanostructures, carriers of monomers, or catalysts. The possibility of patterning different kinds of particles on the same substrate opens the pathway for novel combinatorial designs and novel technologies. One of the examples of such technologies is the synthesis of peptide arrays with amino acid particles. This review examines the known methods of combinatorial particle patterning via static electrical and magnetic fields, laser radiation, patterning by synthesis, and particle patterning via chemically modified or microstructured surfaces. An overview on combinatorial particle patterning is provided, examining the known methods via electrical and magnetic fields, laser radiation, and extending them with novel approaches. Solid particles as carriers of monomers can be used to synthesize molecular libraries, such as peptide arrays. The possibility of patterning different kinds of particles on the same substrate opens the pathway for novel technologies.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/adfm.201703511

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