3 years ago

Thermal Rearrangement of Sulfamoyl Azides: Reactivity and Mechanistic Study

Thermal Rearrangement of Sulfamoyl Azides: Reactivity and Mechanistic Study
Xiaodong Zou, Guigen Li, Jiaqi Zou, Lizheng Yang, Hongjian Lu
The rearrangement of sulfamoyl azides under thermal conditions to form a C–C bond while breaking two C–N bonds is reported. Mechanistic study shows that this reaction goes through a Curtius-type rearrangement to form a 1,1-diazene, then which rearranges possibly through both a concerted rearrangement process and a stepwise radical process. This rearrangement could be used in the synthesis of complex biologically active molecules, such as sterols, and piperine derivatives.

Publisher URL: http://dx.doi.org/10.1021/acs.joc.7b00308

DOI: 10.1021/acs.joc.7b00308

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.