3 years ago

Palladium-Catalyzed Synthesis of Conjugated Allenynes via Decarboxylative Coupling

Palladium-Catalyzed Synthesis of Conjugated Allenynes via Decarboxylative Coupling
Jon A. Tunge, Mary K. Smith
A new strategy to access conjugated allenynes via a decarboxylative coupling of propargyl esters of propiolates has been developed. In this process, allenyl-palladium intermediates are coupled with acetylides that are generated in situ to form the conjugated allenynes. Finally, the coupling is demonstrated to be highly stereospecific, providing a route to enantioenriched allenes.

Publisher URL: http://dx.doi.org/10.1021/acs.orglett.7b01751

DOI: 10.1021/acs.orglett.7b01751

You might also like
Never Miss Important Research

Researcher is an app designed by academics, for academics. Create a personalised feed in two minutes.
Choose from over 15,000 academics journals covering ten research areas then let Researcher deliver you papers tailored to your interests each day.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.