5 years ago

Efficient Modular Synthesis of Substituted Borazaronaphthalene

Efficient Modular Synthesis of Substituted Borazaronaphthalene
Jing-Hui Yang, Jie-Yu Wang, Qi-Ran Chen, Sheng Tang, Fang-Dong Zhuang, Jian Pei, Ji-Min Han
A highly efficient modular synthetic method for BN-fused polycyclic aromatic hydrocarbons (PAHs) composed of a borazaronaphthalene core along with multiple functionalized sites is reported. The halogenated 2,1-borazaronaphthalene cores are constructed through a ring-closing reaction between o-ethynylaniline derivatives and boron halides. The controllable halogen substituents make further derivatization of 2,1-borazaronaphthalene cores feasible by using metal-catalyzed cross-coupling reactions. On the basis of the carefully designed precursors, various functional aromatic rings can be fused to the azaborine core via a one-pot nucleophilic tandem reaction, affording previously inaccessible PAHs in moderate yields.

Publisher URL: http://dx.doi.org/10.1021/acs.organomet.6b00811

DOI: 10.1021/acs.organomet.6b00811

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.