3 years ago

Fishing for key players in ER-mitochondrial contacts.

Liou, Lin
Endoplasmic reticulum-mitochondrial contacts (EMCs) regulate multiple critical cellular activities, dysregulation of which correlates with various human maladies such as neurodegenerative diseases. A new study makes use of the ascorbate peroxidase proximity-labeling proteomics approach to scrutinize the components of EMCs in live cells, leading to the identification of reticulon 1A as a novel promoter of EMCs.

Publisher URL: http://doi.org/10.1074/jbc.H117.795286

DOI: 10.1074/jbc.H117.795286

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