3 years ago

Dietary Carbohydrates Impair Healthspan and Promote Mortality

Dietary Carbohydrates Impair Healthspan and Promote Mortality
Meenakshi Ravichandran, Michael Ristow, Gerald Grandl

The prospective cohort study, named PURE, found that in >135,000 participants from 18 countries, nutritive carbohydrates increase human mortality, whereas dietary fat reduces it, requesting a fundamental change of current nutritional guidelines. Experimental evidence from animal models provides synergizing mechanistic concepts as well as pharmacological options to mimic low-carb or ketogenic diets.

Publisher URL: http://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)30562-4

DOI: 10.1016/j.cmet.2017.09.011

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