Angewandte Chemie - International Edition
Angewandte Chemie - International Edition
5 years ago

Ceria–Zirconia Nanoparticles as an Enhanced Multi-Antioxidant for Sepsis Treatment

Ceria–Zirconia Nanoparticles as an Enhanced Multi-Antioxidant for Sepsis Treatment
Taeghwan Hyeon, Seung-Hoon Lee, In-Young Choi, Changyeong Song, Hyek Jin Kwon, Taeho Kim, Dong-Wan Kang, Wookjin Yang, Min Soh, Han-Gil Jeong, Seungmin Baik, Dokyoon Kim, Chi Kyung Kim, Seul-Ki Ki, Do Yeon Kim
Ceria–zirconia nanoparticles, 2 nm in size and with an increased Ce3+ ratio, exhibit greatly enhanced scavenging performance for reactive oxygen species (ROS). In their Communication (DOI: 10.1002/anie.201704904), S.-H. Lee, T. Hyeon, et al. report the superiority of Ce0.7Zr0.3O2 nanoparticles in regulating inflammatory cells. They work as a potent ROS scavenger for multiple organ dysfunction in sepsis by reducing the mortality and inflammatory responses.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/anie.201706482

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