3 years ago

Metabolic Engineering for Advanced Biofuels Production and Recent Advances Toward Commercialization

Metabolic Engineering for Advanced Biofuels Production and Recent Advances Toward Commercialization
Taek S. Lee, Corey W. Meadows, Aram Kang
Research on renewable biofuels produced by microorganisms has enjoyed considerable advances in academic and industrial settings. As the renewable ethanol market approaches maturity, the demand is rising for the commercialization of more energy-dense fuel targets. Many strategies implemented in recent years have considerably increased the diversity and number of fuel targets that can be produced by microorganisms. Moreover, strain optimization for some of these fuel targets has ultimately led to their production at industrial scale. In this review, the recent metabolic engineering approaches for augmenting biofuel production derived from alcohols, isoprenoids, and fatty acids in several microorganisms are discussed. In addition, the successful commercialization ventures for each class of biofuel targets are discussed. Since the recent maturity of commercial ethanol production, several new biofuel targets have been successfully produced on commercial scale. In this review, the authors address recent scientific advances in metabolic engineering toward scale up of various targets and highlight several successful commercial ventures.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/biot.201600433

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