5 years ago

Formation and stability of anthocyanins-loaded nanocomplexes prepared with chitosan hydrochloride and carboxymethyl chitosan

Formation and stability of anthocyanins-loaded nanocomplexes prepared with chitosan hydrochloride and carboxymethyl chitosan
Anthocyanins as food additives have attracted increasing interest from the food industries, due to its potential health-related functionalities. However, it is low stability to limit its applications in foods. In this work, nanocomplexes of chitosan hydrochloride (CHC), carboxymethyl chitosan (CMC) and anthocyanins (ACNs) were fabricated through electrostatic interaction to improve the stability of ACNs. At the optimal ratio of 1.2 g CHC to 1.0 g CMC (w/w, 8 mg of ACNs), the ACNs-loaded CHC/CMC nanocomplexes showed high encapsulation efficiency (44.0%) with a preferred particle size (178.1 nm), good stability (+25.6 mV) and acceptable polydispersity index (PDI, 0.315). The content and encapsulation efficiency of individual anthocyanin were estimated by UPLC analysis. The cross-linking interactions between the chitosan derivatives (CHC/CMC) and anthocyanins were confirmed by FT-IR spectroscopy. Furthermore, the spherical structure of ACNs-loaded CHC/CMC nanocomplexes was verified by transmission electron microscopy (TEM). Differential scanning calorimetry (DSC) analyses showed that onset temperature and gelatinization enthalpy of ACNs-loaded CHC/CMC nanocomplexes increased with the introduction of ACNs into the chitosan derivatives. Compared with the ACNs aqueous solution (unencapsulated form), the ACNs-loaded CHC/CMC nanocomplexes (encapsulated form) showed a higher stability when placed in different conventional storage temperature, various l-ascorbic acid (AA) concentration, varying pH or white fluorescent light. The results indicate that these nanocomplexes represent potential food ingredients associated with stable anthocyanins, which exhibits great potential for functional foods and nutraceutical applications.

Publisher URL: www.sciencedirect.com/science

DOI: S0268005X17302898

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.