3 years ago

Highly K+-Selective Fluorescent Probes for Sensing of K+ in Living Cells

Highly K+-Selective Fluorescent Probes for Sensing of K+ in Living Cells
Pablo Wessig, Peter Müller, Monique Mertens, Hans-Jürgen Holdt, Janine Riemer, Thomas Schwarze
Coupling of K+ selective N-(o-iso-propoxy)phenylaza-18-crown-6 with [1,3]dioxolo[4,5-f][1,3]benzo-dioxole ester fluorophore yields a new fluorescent probe for the sensing of K+ by increasing the averaged fluorescence decay time (τf(av)). This fluorescent tool is a good candidate for a reliable analysis of physiologically relevant K+ levels by fluorescence lifetime imaging microscopy (FLIM) in vivo. More information can be found in the Communication by P. Wessig, H.-J. Holdt et al. (DOI: 10.1002/chem.201703799).

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201704466

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