3 years ago

Development of a series of bis-triazoles as G-quadruplex ligands

Development of a series of bis-triazoles as G-quadruplex ligands
Christopher J. Moody, Tracey D. Bradshaw, Charles A. Laughton, Maysaa M. Saleh
Maintenance of telomeres - specialized complexes that protect the ends of chromosomes - is provided by the enzyme complex telomerase, which is a key factor that is activated in more than 80% of cancer cells, but absent in most normal cells.

Publisher URL: http://feeds.rsc.org/~r/rss/ra/~3/w-aYrAzmtv8/C7RA07257K

DOI: 2017/RA/C7RA07257K

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