Tetrahedron
Tetrahedron
5 years ago

A synthesis of tiruchanduramine and a reinvestigation of its glycosidase inhibitory activity

A synthesis of tiruchanduramine and a reinvestigation of its glycosidase inhibitory activity
Tiruchanduramine 1 was prepared using a convergent strategy with the longest linear sequence being eight steps. Synthetic 1, displayed a broader range of inhibition than reported previously and, in addition to α-glucosidases, 1 also inhibits almond β-glucosidase, β-galactosidase and β-N-acetylglucosaminidase from jack bean.

Publisher URL: www.sciencedirect.com/science

DOI: S0040402017306270

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