Germline Genome Protection on an Evolutionary Treadmill
Preservation of genome integrity is a conserved, essential function, yet genome defense machinery evolves rapidly. In this issue of Developmental Cell, Parhad et al. (2017) harness an evolution-guided approach to define the genetic determinants of genome defense and to reveal the molecular and cellular mechanisms shaped by adaptive evolution.
Publisher URL: http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30780-3
DOI: 10.1016/j.devcel.2017.09.021
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